The discovery of angiogenic growth factors: the contribution of Italian scientists
نویسنده
چکیده
Angiogenesis is regulated, under both physiological and pathological conditions, by numerous "non-classic" pro-angiogenic factors, including fibroblast growth factor-2 (FGF-2), vascular endothelial growth factor (VEGF), and placental growth factor (PlGF), and "non-classic" pro-angiogenic factors, including granulocyte colony stimulating factor (G-CSF), granulocyte macrophage colony stimulating factor (GM-CSF), and erythropoietin (EPO). In the context of the most important discoveries in this field, this review article summarizes the important role played by the Italian scientists in the course of the last twenty years.
منابع مشابه
Human Trophoblast Progenitor Cells Express and Release Angiogenic Factors
Trophoblast stem cells develop from polar trophoectoderm and give rise to the cells that generate the placenta. Trophoblast cells are responsible for the uterinal invasion and vascular remodeling during the implantation of the embryo. However this knowledge is not yet to be confirmed for trophoblast progenitor cells (TPCs). In this study, we aimed to demonstrate that human TPCs (hTPCs) express ...
متن کاملCarbon nanotubes via different catalysts and the important factors that affect their production: A review on catalyst preferences
This review paper provides researcherwith a comprehensive information about the Carbon Nano tubes and the catalyst parameters that influences theproduction and morphology of the of Carbon Nano tubes.Carbon nanotubes, referred to as CNTs, are one of the most important materials used in electrical, mechanical, thermal, chemical and textile industries. Since discovery of CNTs in 1991, many scienti...
متن کاملThe Anti-Proliferative and Anti-Angiogenic Effect of the Methanol Extract from Brittle Star
Background: Anti-angiogenic therapy is a crucial step in cancer treatment. The discovery of new anti-angiogenic compounds from marine organisms has become an attractive concept in anti-cancer therapy. Because little data correlated to the pro- and anti-angiogenic efficacies of Ophiuroidea, which include brittle star, the current study was designed to explore the anti-angiogenic potential of bri...
متن کاملCarbon nanotubes via different catalysts and the important factors that affect their production: A review on catalyst preferences
This review paper provides researcherwith a comprehensive information about the Carbon Nano tubes and the catalyst parameters that influences theproduction and morphology of the of Carbon Nano tubes.Carbon nanotubes, referred to as CNTs, are one of the most important materials used in electrical, mechanical, thermal, chemical and textile industries. Since discovery of CNTs in 1991, many scienti...
متن کاملA Study on the Serum Levels of Angiogenic Factors in Response to Acute Long-term Submaximal Exercise in Sedentary Men
Introduction: Exercise training increases skeletal muscle capillary density, but the molecular mechanisms of this process are not yet clear. The aim of the present study was to investigate the effect of acute long- term submaximal exercise on serum vascular endothelial growth factor (VEGF) as the main angiogenic factor, and matrix metalloproteinases 2 and 9 ( MMP-2 and MMP-9), as the degradi...
متن کامل